Increasing severity of constriction on angiography correlated with larger pressure gradients at rest and during exercise (P < 0.0001). Twelve healthy volunteers (mean age 32 years, range 17-56) provided reference values for cuff pressures after exercise.Īll patients with a difference in cuff pressure at rest of 35 mm Hg or more had a difference in invasive pressure of 35 mm Hg or more. The degree of constriction was assessed by angiography. Invasive pressures and cardiac output by thermodilution were recorded during catheterisation while patients were at rest and during and after supine bicycle exercise. Arm and ankle blood pressure were measured with a cuff at rest and 1-10 minutes after exercise. The patients exercised submaximally while supine, seated on a bicycle, and walking on a treadmill, as well as exercising maximally on a treadmill. Eight had undergone previous coarctation surgery, of whom five had received vascular grafts and three end to end anastomoses. To evaluate the difference in systolic blood pressure at the arm and ankle at rest and after various exercise tests for the assessment of aortic coarctation.Ģ2 patients (mean age 33 years, range 17-66) were investigated on the suspicion of having haemodynamically significant aortic coarctation.
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